Tirzepatide vs Semaglutide: Cost, Results, and What You Actually Pay
Tirzepatide and semaglutide both work. One posted 20% average body weight loss, the other 15%. Here is what you pay for each.
Tirzepatide and semaglutide are both GLP-1 receptor agonists that help with weight loss. The trials showed tirzepatide posted about 20% average body weight loss and semaglutide about 15%. Both work, both are injected weekly, and both are available online from PepHaūs. The price difference is smaller than most people think.
Is this you?
Is this you?
This could be for you if the scale will not move no matter what you try, your jeans do not fit like they used to, you get tired after every meal, you snack at night without even being hungry, the 3 pm energy crash hits every day, you want to feel like yourself again, you have no time for clinic visits, shift work never lines up with clinic hours, or you want results backed by real trials. If you nodded at two or three of those, keep reading.
What the trials showed
Tirzepatide is a dual-action GLP-1 and GIP receptor agonist. The clinical trials posted about 20% average body weight loss over 72 weeks. Semaglutide is a GLP-1 receptor agonist. The trials showed about 15% average body weight loss over the same period. Both were tested as weekly injections, both help most people feel full faster and eat less, and both can help reduce food noise between meals.
What you pay for tirzepatide
Tirzepatide from PepHaūs is $239 the first month, $227 on the 3-month plan, and $215 on the 6-month plan. Provider visit and shipping included. No separate doctor fee. The price covers the intake, the provider visit, the medication compounded by a U.S.-licensed pharmacy, and delivery to your door.
Ready when you are. Ten minutes on your phone.
Start my online visitWhat you pay for semaglutide
Semaglutide from PepHaūs is $169 the first month, $160 on the 3-month plan, and $152 on the 6-month plan. Provider visit and shipping included. Same setup as tirzepatide. One price, everything covered.
How to choose between them
Start with your provider. The intake asks about your weight goals and medical history. Your provider recommends the compound that fits your situation. Some people start with semaglutide because the entry price is lower. Some start with tirzepatide because the trial results were higher. Your provider can help you switch if the first choice does not feel right.
The real thing vs the rest
Gummies and GLP-1 pills are not the same thing
GLP-1 gummies and oral drops were never in the trials. Swallow a pill and your gut digests most of it. About 1% reaches your blood. Inject semaglutide or tirzepatide and about 80% reaches your system. That gap is why the injectable forms posted 15% and 20% average body weight loss. A gummy cannot match that.
The real thing vs the rest
A gummy cannot do this. Not even close.
Weight loss gummies, so called GLP-1 pills and liposomal drops sold on social media were never in the clinical trials. Injectable tirzepatide and semaglutide were. Overseas research-only vials have no pharmacy and no physician behind them.
Weight loss gummies
0 mg
No GLP-1 medication inside. Fiber and plant extracts.
Pills and drops
about 1%
Swallow it and about 1 of every 100 units reaches your blood.
Weekly injection
about 80%
Absorbed from the fat layer. Nothing in the way.
Swallow it: about 1% reaches your blood. Inject it: about 80% does. Same comparison we show on our homepage.
| What you get | PepHaūs prescription | Gummies and “GLP-1 pills” | Grey market vials |
|---|---|---|---|
| Studied in clinical trials | |||
| Average loss in clinical trials | About 15% to 20% of body weight | None reported | Unknown |
| Physician licensed in your state | |||
| U.S.-licensed pharmacy | |||
| Tested product, cold shipped | |||
| Provider visit included | |||
| Dose tuned to you |
Pricing
What it costs
Tirzepatide from $215 a month on the 6-month plan. Semaglutide from $152 a month on the 6-month plan. Provider visit and shipping included. No insurance billing, no hidden fees. The first month costs more because it includes the intake and the provider visit setup. After that, the monthly price drops on the 3-month and 6-month plans.
Pricing in your door
One price. Provider visit, medication and shipping included.
- First month$239
- 3-month plan$227/mo
- 6-month plan$215/mo
- First month$169
- 3-month plan$160/mo
- 6-month plan$152/mo
- Provider visit
- Medication
- Cold shipping to your door
- Refills on a schedule
- Care team messaging
- Cancel anytime online
LegitScript certified
A real U.S. pharmacy vs the grey market
Overseas research-only vials say "not for human use" right on the label. No pharmacy, no provider, no testing. PepHaūs is LegitScript certified. Every dose is compounded by a U.S.-licensed pharmacy, prescribed by a U.S.-licensed physician, and shipped from a facility that follows U.S. standards.
FAQ
FAQ
Which one works better, tirzepatide or semaglutide?+
Tirzepatide posted about 20% average body weight loss in trials, semaglutide about 15%. Both work for most people. Your provider can help you choose.
Can I switch from semaglutide to tirzepatide?+
Yes. Talk to your care team. If your provider agrees, the switch happens on your next refill.
How fast does it ship?+
About two to three business days after your provider approves. Refills ship on schedule so you never run out.
Do I need insurance?+
No. PepHaūs does not bill insurance. You pay the monthly price and that covers everything.
What if I want to try both?+
Start with one. Your provider can switch you to the other if the first choice does not feel right. The switch happens on your next refill. If you are ready to start, head to /start and complete the intake. Takes about ten minutes and you hear back the same day. Read more about tirzepatide or how to get semaglutide online .
Start your visit from your phone
Ten minutes on your phone. A physician licensed in your state. A box on your porch in 2 to 3 business days.
See if you qualifyYour care team
Every PepHaus visit is reviewed by a licensed physician from the Wasef Health Group provider network. A doctor reads your intake, decides if treatment fits, and sets your plan.
Meet the physiciansThis article is educational and is not medical advice. Compounded medications are not FDA-approved. Treatment requires evaluation by a licensed provider.