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Semaglutide
6-Month Plan · $152/mo
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LegitScript certified
What semaglutide does
★★★★★5.0 on Google from PepHaus patients
Weekly injectionProvider prescribedPrescribedSave $101 on 6 months

Semaglutide

Prescribed online. One shot a week. The most clinically studied GLP-1 for weight management, for quieter cravings, portions that satisfy, and energy that holds steady through the afternoon. Prescribed by a U.S. licensed provider and filled by VialsRX, a licensed U.S. 503A pharmacy. Everything included. Read the complete semaglutide guide.

$152/mo$169on the 6-month plan · billed $912.60
Best value: 6-month planSave $101
6-Month PlanLowest price. One review, then quiet. $152/mo$169/mo
Quarterly PlanSave $25 vs monthly $160/mo$169/mo
MonthlyMost flexible $169/mo
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★★★★★5.0 on Google from PepHaus patients
  • Cravings go quiet. The food noise settles.
  • Full faster, full longer. Smaller portions satisfy.
  • Steadier energy. Fewer afternoon crashes.
  • Give it time. The strongest results show at 4 to 6 months.
  • Online provider visit and ongoing care in the portal
  • Compounded semaglutide, a 30-day supply
  • Syringes, alcohol swabs and first-dose instructions
  • Free cold shipping on every order
  • One small shot a week, same day each week
  • Belly or upper thigh. Rotate the spot.
  • Refrigerate at 36 to 46°F. Do not freeze.
  • Your provider adjusts your dose. Your price stays the same.
  • Prescription only. A licensed provider reviews your health history first.
  • Compounded semaglutide is not FDA-approved. Its safety and effectiveness have not been independently established by the FDA.
  • Most patients report nausea, reduced appetite and mild GI changes during the first weeks of each new dose. These usually fade.
  • Compounded medications are prescribed only when a licensed provider determines that a commercially available, FDA-approved alternative is not clinically appropriate for you.
LegitScript certifiedU.S. licensed providersCertificate of AnalysisFree cold-chain shipping

The absorption problem.

Swallow it: about 1% reaches your blood.
Inject it: about 80% does.

Oral semaglutideSwallowed daily tablet1 of 100 arrives
Injected semaglutideWeekly subcutaneous shot80 of 100 arrive
Diagram: a tablet breaking down through the stomach, gut and liver with one droplet left, versus a shot through the skin delivering a full droplet
Swallowed1Stomach acid2Enzymes3Gut wall4Liver
Injected1Skin2Fat layer3Blood
~1%arrivesoral semaglutide
80%arrivessubcutaneous semaglutide
Pile of orange gummies
Weight loss gummies
0 mg

No GLP-1 medication inside. Fiber and plant extracts.

Tablets and a capsule
Weight loss pills
~1%

Even oral semaglutide: about 1% of the dose reaches your blood.

Small insulin syringe on linen
Weekly injection
80%

Semaglutide, absorbed from the fat layer. Nothing in the way.

The supplement shelf vs. semaglutide.

PepHaus semaglutide PepHaus compounded semaglutide vial
The supplement stack~$250/mo
  • Greens, tea, berberine, fat burner
  • Fiber, gummies, probiotic, collagen
  • Ten daily routines to remember
  • No provider, no prescription, no titration
PepHaus, 6-month plan$152/mo
  • Semaglutide, one weekly injection
  • Provider visit and slow, personalised titration
  • Supplies, CoA, free cold shipping
  • One of the most-studied GLP-1 treatments
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Supplement stack pricing is illustrative of typical retail. Prescription only; a licensed provider decides if semaglutide is appropriate for you. Compounded semaglutide is not FDA-approved. Individual results vary.

Licensed physicians review every order.

Every PepHaus visit is reviewed by a licensed physician from the Wasef Health Group provider network. A doctor reads your intake, decides if treatment is right for you, and sets your plan.

Dr. Michael Wasef, MD
Dr. Michael Wasef, MDInternal medicine · Founder, Wasef Health
Dr. Andrew Sakla, DO
Dr. Andrew Sakla, DOInternal medicine
Dr. James Teet, DO
Dr. James Teet, DOFamily medicine

Also caring for PepHaus patients: Dr. David Wasef, MD, Dr. Asad Khan Niazi, MD, and Dr. Constantin Chikando, MD.

Meet the physicians →

Physicians are affiliated with Wasef Health Group.

What the first months looked like.

★★★★★5.0 on Googlefrom PepHaus patient reviews
BeforeDayna before starting with PepHaus
AfterDayna after starting with PepHaus
Dayna · Tirzepatide★★★★★
★★★★★

"I've been a customer for a few months and love how easy PepHaus makes the whole process, even when changing my subscription. My first order arrived in 2 days, and I heard from the physician within a few hours of submitting my request."

DDaynaGoogle review
★★★★★

"This was such a great experience. It was easy to schedule and meet with the provider."

NNicole M.Google review
★★★★★

"Premium product start to finish. They make the process extremely easy. Couldn't recommend more."

JJonathan T.Google review

Photos are from real PepHaus patients who consented to share them. The treatment each patient used is labelled. Individual results vary and are not guaranteed.

It goes into the fat layer. That is the point.

A tiny needle places the dose just under the skin, in the fat layer. From there it is absorbed slowly, which is why one shot lasts a week.

Diagram of skin, fat layer, and blood vessels with a short needle stopping in the fat layer
Skin
Fat layer. The dose goes here.
Blood vessels. Slow, steady pickup.
Muscle. Not involved.
A grain of rice, a short fine insulin needle, and a strand of hair side by side

Smaller than you think.

The needle you are picturing is not the needle you would use.

1 in 8 U.S. adults have taken a GLP-1 medication. Most say the needle stops being a thing after the first few.

One fixed price at any dose.

MonthlyBilled monthly$169/mo
Quarterly Save $25Billed $481.65 every 3 months$160/mo
6-Month Best valueBilled $912.60 every 6 months$152/mo
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What it does

Semaglutide is a GLP-1 receptor agonist. Activating GLP-1 receptors helps you feel full sooner, slows stomach emptying and reduces overall food intake. Eating less takes less effort.

  • Cravings go quiet. The constant food noise settles down.
  • Full faster, full longer. Smaller portions actually satisfy you.
  • Steadier energy. Fewer afternoon crashes and snack urges.
  • Backed by research. One of the most-studied GLP-1 treatments for weight loss.

Dosing is personalised, never one-size-fits-all. Your provider starts you low, holds at each step until your body adjusts, and advances only when the current dose is tolerated.

Breakdown of what semaglutide does in the body

No insurance. No clinic. No waiting room.

A U.S. licensed provider reviews your intake, usually within 24 hours.

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Straight answers.

Is compounded semaglutide FDA-approved?
No. Compounded medications are prepared by a licensed U.S. pharmacy for your specific prescription and are not FDA-approved as a finished product. The active ingredient is the same GLP-1 used in approved treatments. Your provider reviews whether it is appropriate for you.
How is compounded semaglutide different from the brand-name pen?
It uses the same active GLP-1 ingredient, prepared by a licensed U.S. compounding pharmacy and shipped directly to you, typically at a lower, fixed monthly price.
How does dosing work?
Your provider starts you low and adjusts gradually based on how your body responds. Each step is held until your body adjusts, and the dose advances only when the current one is tolerated. Your price stays the same at every dose.
What if my provider decides semaglutide is not right for me?
If it is not a fit, you are not charged for the medication. Your provider may suggest an alternative such as tirzepatide.
Can I switch from tirzepatide to semaglutide?
Yes. Message your provider through your dashboard and they will help you transition safely if it is appropriate for you.
What ships with my first order?
Your medication plus everything you need to get started: pre-measured BD insulin syringes, individually wrapped alcohol swabs, a Certificate of Analysis and simple first-dose instructions, with free expedited, temperature-controlled shipping.
Who fills the prescription?
VialsRX, a licensed U.S. 503A compounding pharmacy partnered with PepHaus. Every vial ships with a Certificate of Analysis showing purity and concentration.
Does insurance cover this?
No. PepHaus is cash-pay. The price you see covers the medication, supplies, provider review and shipping. No insurance billing.
Is semaglutide available in my state?
PepHaus serves patients in all 50 U.S. states plus the District of Columbia through licensed provider and pharmacy partners. You confirm eligibility during your online visit.
Can I cancel anytime?
Yes. You can manage or cancel your plan anytime from your dashboard, no phone call.

Four steps. No waiting room.

Step 1: a five minute online visit on your phone, no appointment
STEP 01
5-minute online visit

A short online intake. No waiting room, no phone tag.

Step 2: a U.S. licensed provider in your state reviews your intake
STEP 02
Provider review

A U.S. licensed provider decides if semaglutide is appropriate. $0 charged at this step.

Step 3: medication compounded by a licensed U.S. pharmacy and shipped cold to your door
STEP 03
Shipped cold

Compounded by VialsRX, a licensed U.S. pharmacy, to your door.

Step 4: message your PepHaus care team anytime in the patient portal
STEP 04
Care on tap

Message your care team anytime in the portal.

Ready when you are.

One weekly shot, prescribed by a U.S. licensed provider and shipped cold to your door.

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Start my order6-Month Plan · $152/mo
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