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Sermorelin and NAD+: Pairing Two Peptides for Recovery and Energy

Pair sermorelin and NAD+ for recovery during sleep and sustained energy through the day.

PepHaūs Clinical TeamReviewed by the PepHaūs Clinical TeamOctober 26, 2026
Sermorelin and NAD+ peptide injections for recovery and energy

Sermorelin and NAD+ work well together because they support recovery and energy through different pathways. Sermorelin signals your pituitary to release growth hormone in its natural nightly pulse while NAD+ powers cellular energy production and mitochondrial function.

Is this you?

Is this you?

You are looking for something that helps with recovery from training and keeps your energy steady during the day. You have heard about peptides for longevity but do not want to pick just one. You want deeper sleep and better focus without taking a dozen different supplements. You train or stay active and notice recovery takes longer than it used to. You want something backed by research but simple to use. Your energy dips in the afternoon and you are tired of relying on caffeine. If you nodded at two or three of those, keep reading.

Sermorelin, prescribed online from $143/mo

A nightly at home shot. Provider visit and shipping included. Nothing charged unless you are prescribed.

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How sermorelin works

Sermorelin is a growth hormone releasing hormone analog that signals the pituitary to release the body's own growth hormone in its natural nightly pulse. It is not HGH and does not raise testosterone. You inject sermorelin once a day before bed and it works with your body's rhythm. Growth hormone is released during deep sleep when recovery happens. Many people report better sleep quality within the first two weeks. The injection is subcutaneous with a small insulin needle under the skin of your abdomen or thigh. It takes about 30 seconds. Over eight to twelve weeks people report feeling more rested when they wake up and notice muscles recover faster after training. Sermorelin supports lean body composition and pairs with training and protein. Muscle claims are limited to supports recovery and supports deeper sleep which is when growth hormone is released. You will not see pounds or inches advertised because those numbers depend on diet and training.

How NAD+ works

NAD+ is a coenzyme your cells need for energy production. Every cell uses it to turn food into energy through the mitochondria. NAD+ levels decline with age starting in your thirties. NAD+ injections restore those levels directly. You inject NAD+ one to three times a week depending on your dose. The injection is intramuscular or subcutaneous. Most people start with one 100mg injection per week and adjust up to 200mg or 300mg based on how they feel. Within a few days people report sharper focus and steadier energy. NAD+ does not give you a caffeine buzz. It powers your cells so you have sustained energy through the day. Clinical studies show NAD+ supports mitochondrial function and cellular repair. Many people report less brain fog and better mental clarity by the second week.

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Pairing them together

Sermorelin and NAD+ target different systems. Sermorelin works on growth hormone release during sleep. NAD+ powers cellular energy during the day. Together they cover recovery and energy in a way one alone cannot. You take sermorelin at night before bed. You take NAD+ in the morning or early afternoon. The timing keeps them working on their own pathways. People who use both report feeling recovered in the morning from sermorelin and sustained focus through the day from NAD+. Training sessions feel productive and the afternoon energy dip disappears. This combination is popular with people over 35 who stay active and want to feel the way they did a decade ago. PepHaus offers both prescribed together after a provider review. You can start one and add the other later or begin with both at the same time.

The real thing vs the rest

Gummies and GLP-1 pills are not the same thing

Peptide gummies and pills were never in the clinical trials. They are sold over the counter without a prescription or provider oversight. When you swallow a peptide about 1% reaches your blood because stomach acid breaks it down. When you inject a peptide about 80% reaches your blood. Injectable sermorelin and NAD+ from a licensed pharmacy deliver the dose that was studied. Gummies and pills do not. The grey market sells research vials online with no pharmacy and no provider. Those vials are not compounded for human use and have no testing. A U.S. licensed pharmacy compounds sermorelin and NAD+ under sterile conditions with every batch tested. A licensed physician reviews your health and prescribes the right dose for you. That is the difference between a treatment and something bought off a website.

The real thing vs the rest

A capsule cannot do this.

An injection prescribed by a physician puts the compound where it needs to go. A capsule or drink from an ad mostly does not survive digestion, and a grey market vial has nobody standing behind it.

Gummies and drinks

0 mg

No prescription compound inside.

Liposomal capsules

about 1%

Swallow it and about 1 of every 100 units reaches your blood.

Weekly injection

about 80%

Absorbed from the fat layer. Nothing in the way.

Swallow it: about 1% reaches your blood. Inject it: about 80% does. Same comparison we show on our homepage.

What you getPepHaūs prescriptionLiposomal capsules and drinksGrey market vials
Goes straight into your systemUnknown
Physician licensed in your state
U.S.-licensed pharmacy
Tested product, cold shipped
Provider visit included
Dose tuned to you

Pricing

What it costs

Sermorelin from PepHaus is $159 a month at the starting dose and drops to $151 then $143 as you stay on it. NAD+ is $199 a month at 100mg per week and drops to $189 then $179. If you take both together the combined price is $358 a month at the start and drops to $322 over time. Everything is included. The provider visit is included. Shipping is free and expedited. There is never a doctor fee or membership. You pay one price for the peptide and the care that comes with it. Labs are not required to start but your provider may recommend them based on your health. Individual results vary and some people see changes faster than others. Compare that to the grey market where you pay for a vial with no idea what is in it and no one checking if it is safe for you. The cost of doing it right is worth it when your health is on the line.

Pricing in your door

One price. Provider visit, medication and shipping included.

Sermorelin$143/moon the 6-month plan
  • First month$159
  • 3-month plan$151/mo
  • 6-month plan$143/mo
See sermorelin→
Included in every plan
  • Provider visit
  • Medication
  • Cold shipping to your door
  • Refills on a schedule
  • Care team messaging
  • Cancel anytime online
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LegitScript certified

A licensed U.S. pharmacy vs the grey market

PepHaus sources sermorelin and NAD+ from a U.S. licensed 503A compounding pharmacy. Every batch is tested for sterility and potency. A licensed physician prescribes it after reviewing your health and goals. You get follow up care and can message your provider anytime. The grey market sells research vials online from overseas with no pharmacy and no testing. Research vials are labeled not for human use. There is no provider and no one checking if it is safe for you. If something goes wrong you have no recourse. The price might look lower but the risk is not worth it. A licensed pharmacy and a licensed physician mean you are using a treatment compounded for you and prescribed after someone reviewed your health.

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FAQ

FAQ

Can I take sermorelin and NAD+ at the same time of day?+

You can but sermorelin works best at night before bed because it signals growth hormone release during sleep. NAD+ works best in the morning or early afternoon because it powers daytime energy. Spacing them out lets each one work on its own schedule. Many people inject sermorelin before bed and NAD+ after breakfast or before lunch.

Do I need a prescription for sermorelin and NAD+?+

Yes. Both are prescription peptides compounded by a U.S. licensed pharmacy. A licensed physician reviews your health and prescribes the right dose for you. PepHaus connects you with a provider online and most people get a response within 24 hours. The review takes a few minutes and you do not need labs to start.

How long until I notice results from sermorelin and NAD+?+

Most people report better sleep from sermorelin within two weeks and improved recovery within four to six weeks. NAD+ works faster. Many people notice sharper focus and steadier energy within a few days of the first injection. Individual results vary and some people see changes sooner than others. Give it at least eight weeks to feel the full benefit of both.

Can I add sermorelin and NAD+ to my current supplement routine?+

Yes. Sermorelin and NAD+ work alongside vitamins and protein supplements. They are not replacements for a healthy diet or training. Many people take creatine or omega-3s with sermorelin and NAD+ without any interaction. If you take prescription medications tell your provider during the review so they can check for interactions.

Do sermorelin and NAD+ raise testosterone?+

No. Sermorelin signals your pituitary to release growth hormone. It does not raise testosterone levels. NAD+ powers cellular energy and does not affect testosterone. PepHaus does not sell TRT or HGH. If you are looking for testosterone replacement therapy you will need to find a clinic that specializes in that. Sermorelin and NAD+ support recovery and energy through their own pathways.

Can women take sermorelin and NAD+ together?+

Yes. Both peptides work for men and women. The benefits are the same. Better sleep and recovery from sermorelin and sustained energy and focus from NAD+. Dosing is based on your weight and goals and your provider will prescribe the right amount for you. Many women over 35 use this combination for energy and recovery.

Where do I inject sermorelin and NAD+?+

Sermorelin is injected subcutaneously under the skin of your abdomen or thigh with a small insulin needle. NAD+ can be injected intramuscularly in your thigh or deltoid or subcutaneously in your abdomen. The injections take less than a minute each. Your provider will send instructions and most people feel comfortable after the first few times. If you have questions you can message your provider anytime. Sermorelin and NAD+ together cover recovery and energy in a way one peptide alone cannot. Sermorelin works at night during sleep to support growth hormone release and recovery. NAD+ works during the day to power cellular energy and focus. Together they help you feel rested when you wake up and sharp through the afternoon. PepHaus prescribes both after a provider review from a U.S. licensed pharmacy. Start today at thepephaus.com/sermorelin and thepephaus.com/nad or read more at the Sermorelin Guide and NAD+ Guide .

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Ten minutes on your phone. A physician licensed in your state. A box on your porch in 2 to 3 business days.

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Your care team

Every PepHaus visit is reviewed by a licensed physician from the Wasef Health Group provider network. A doctor reads your intake, decides if treatment fits, and sets your plan.

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This article is educational and is not medical advice. Compounded medications are not FDA-approved. Treatment requires evaluation by a licensed provider.