What to know about glutathione.

• Are allergic to glutathione or any of its ingredients (including sulfur-containing compounds)
• Are pregnant, planning to become pregnant, or breastfeeding
• Have severe asthma (rare reports of bronchospasm with high-dose glutathione)
• Have severe liver or kidney impairment without provider supervision

The following risks should be discussed with your provider before starting and monitored throughout treatment:

• Hypersensitivity reactions

  Rare but serious reactions including anaphylaxis and Stevens-Johnson syndrome have been reported. Discontinue and seek emergency care for severe rash, swelling of the face or throat, or difficulty breathing.

• Bronchospasm in asthmatic patients

  High-dose glutathione has been associated with bronchospasm in patients with severe asthma. Use with caution in asthmatic patients.

• Injection-site reactions

  Mild redness, warmth, or itching at the injection site is common and usually resolves within hours.

• Skin lightening

  At higher doses, glutathione may cause gradual skin lightening due to its effect on melanin production. Discuss with your provider if uneven skin tone develops.

• Patients with liver or kidney impairment

  Glutathione is processed by the liver and kidneys. Your provider will assess whether glutathione is appropriate based on your organ function.

Commonly reported side effects of glutathione injections are typically mild:

Symptoms typically improve with time. Your provider will adjust your dose to minimize side effects.