❄❄❄❄❄❄❄❄
Holiday sale: $10 off every order with code HAUS10
MOTS-c
6-Month Plan · $152/mo
LegitScript certified
What MOTS-c does
★★★★★5.0 on Google from PepHaus patients
Subcutaneous injectionInjectionProvider prescribedPrescribedSave $101 on 6 months

MOTS-c

A small peptide shot, a few times a week, studied for cellular energy, workout endurance and healthy aging. MOTS-c is a signal your own mitochondria make, and your body makes less of it with age. Your provider sets the dose and the schedule.

$152/mo$169on the 6-month plan · billed $912.60
Best value: 6-month planSave $101
6-Month PlanLowest price. One review, then quiet. $152/mo$169/mo
Quarterly PlanSave $25 vs monthly $160/mo$169/mo
MonthlyMost flexible $169/mo
★★★★★5.0 on Google from PepHaus patients
  • Energy: studied for how cells make and use energy, the job your mitochondria do all day.
  • Endurance: studied in animal research for exercise capacity and how long muscles keep going.
  • Metabolism: studied for how the body handles fuel during and after training.
  • Healthy aging: MOTS-c levels drop with age, and it is studied as part of longevity research.
  • Online provider visit and ongoing care in the portal
  • Compounded MOTS-c, a 30-day supply
  • Syringes, alcohol swabs and first-dose instructions
  • Free expedited shipping on every order
  • A small shot at home a few times a week, on your provider’s schedule
  • Your provider sets your dose and adjusts it to your response
  • Ships cold and ready to use. No mixing.
  • Prescription only. A U.S. licensed provider reviews your health history first.
  • Compounded MOTS-c is not an FDA approved product, and human research on it is early.
  • Most reports are mild and temporary: redness or warmth at the injection site, and sometimes brief tiredness or a headache on the first dose or two.
  • Your provider screens your full history first. Message them in the portal with any concerns.
  • Available in all 50 states. Eligibility and state availability are confirmed during intake, before any charge.
LegitScript certifiedU.S. licensed providersCertificate of AnalysisFree expedited shipping

A small shot, a few times a week, for cellular energy.

Tablets and a capsule
Research vials online
Unknown

Powder sold for research with no provider, no Certificate of Analysis and no one to set your dose. Not the same thing.

Small insulin syringe on linen
Subcutaneous
Direct

A small shot under the skin delivers MOTS-c directly, in a dose your provider sets and adjusts.

Syringe with linen and prep pad
At home
Simple

A short shot you give yourself at home. No clinic, no mixing, no guessing.

Many patients run MOTS-c alongside NAD+ or a training block for energy support. Others use it on its own as part of a longevity routine. Not sure whether you want MOTS-c or NAD+? The table below shows the difference.

NAD+MOTS-c
What it isA coenzyme every cell uses to turn food into energy.A small peptide your mitochondria make that acts as an energy signal.
Best fitAfternoon slumps, focus, everyday energy.Training energy, endurance, a longevity routine.
Studied forCellular energy, focus, healthy aging.Exercise capacity, how the body uses fuel, healthy aging.
How oftenSeveral times a week.A few times a week, on your provider’s schedule.
PriceFrom $179/moFrom $152/mo

Research vials online vs. a prescription at home.

PepHaus MOTS-c vial PepHaus MOTS-c
Research vials onlineUnknown purity
  • No provider, no prescription, no one to ask
  • Purity and concentration not verified
  • Powder you reconstitute and dose yourself
  • Labeled not for human use
PepHaus, 6-month plan$152/mo
  • MOTS-c, a subcutaneous injection at home
  • Provider review and dose adjustments included
  • Certificate of Analysis on every vial
  • Free expedited shipping, cancel anytime online

Prescription only; a licensed provider decides whether MOTS-c is appropriate for you. Compounded MOTS-c is not an FDA approved product and human research on it is early.

Licensed physicians review every order.

Every PepHaus visit is reviewed by a licensed physician from the Wasef Health Group provider network. A doctor reads your intake, decides if treatment is right for you, and sets your plan.

Dr. Michael Wasef, MD
Dr. Michael Wasef, MDInternal medicine · Founder, Wasef Health
Dr. Andrew Sakla, DO
Dr. Andrew Sakla, DOInternal medicine
Dr. James Teet, DO
Dr. James Teet, DOFamily medicine

Also caring for PepHaus patients: Dr. David Wasef, MD, Dr. Asad Khan Niazi, MD, and Dr. Constantin Chikando, MD.

Meet the physicians →

Physicians are affiliated with Wasef Health Group.

What patients say.

★★★★★5.0 on Googlefrom PepHaus patient reviews
Google review

"Premium product start to finish! They make the process extremely easy. Couldn't recommend more!!!"

JJonathan T.Google review
Google review

"I've been a customer for a few months and love how easy PepHaus makes the whole process, even when changing my subscription. My first order arrived in 2 days, and I heard from the physician within a few hours of submitting my request."

DDaynaGoogle review
Google review

"This was such a great experience. It was easy to schedule and meet with the provider."

NNicole M.Google review

Reviews are from real PepHaus patients. Individual results vary and are not guaranteed.

It goes into the fat layer. That is the point.

A tiny needle places the dose just under the skin, in the fat layer. From there the subcutaneous route releases MOTS-c gradually over hours, which is why most protocols use a small dose a few times a week rather than a large one.

Diagram of skin, fat layer and blood vessels with a short needle stopping in the fat layer
Skin
Fat layer. The dose goes here.
Blood vessels. Slow, steady pickup.
Muscle. Not involved.

What it does

What MOTS-c supports
MOTS-c is a 16 amino acid peptide encoded in your mitochondrial DNA, the small set of genes inside the parts of your cells that make energy. It acts as a signal, telling cells how to handle fuel, especially during exercise and stress. Your body makes less of it as you age. In animal research it has been studied for exercise capacity, how muscles use fuel and markers of healthy aging. Human research is still early.
ENERGYCellular
TRAININGEndurance
AGINGLongevity
DOSINGA few times a week
What to expect over time
Most protocols run a few small shots a week for eight to twelve weeks, then your provider reviews how you feel and decides on the next block. Some patients report steadier energy and easier training within the first few weeks. Others notice little. Human research is early, effects are gradual and patient-specific, and individual results vary.
Who it is for
Adults who train and want more in the tank, people building a longevity routine, and anyone already on NAD+ who wants another layer of energy support. Patients want a provider-led option instead of an unregulated vial. Provider approval is required based on your health profile. Your provider screens your history and anything else you take during intake.
Side effects and safety
Human safety data on MOTS-c is limited. Reports are generally mild and temporary: redness or warmth at the injection site, and sometimes brief tiredness or a headache on the first dose or two. Compounded MOTS-c is not FDA approved, and compounded medications are prescribed only when a licensed provider determines that a commercially available, FDA approved alternative is not clinically appropriate for you.
Breakdown of what MOTS-c does

No insurance. No clinic. No waiting room.

A U.S. licensed provider reviews your intake, usually within 24 hours.

Start my order

Straight answers.

What is MOTS-c?
MOTS-c is a small peptide made from instructions in your mitochondrial DNA. It works as an energy signal inside cells and has been studied for exercise capacity, how the body uses fuel and healthy aging. Human research is still early.
How is MOTS-c different from NAD+?
NAD+ is a coenzyme every cell uses to turn food into energy. MOTS-c is a signal that tells cells how to handle fuel, especially during exercise. NAD+ fits everyday energy and focus. MOTS-c fits training energy and a longevity routine. Many patients run both. Your provider decides.
What is the protocol?
A small subcutaneous injection at home, a few times a week, usually in blocks of eight to twelve weeks. Your provider sets your dose and your schedule based on your intake, and adjusts both based on how you respond. Everything is managed through your dashboard.
What are the common side effects?
Reports are generally mild and temporary: redness or warmth at the injection site, and sometimes brief tiredness or a headache on the first dose or two. Human safety data is limited. Your provider reviews your history first and answers any concerns in the portal.
Can I take MOTS-c with NAD+ or a GLP-1?
Many patients do. Energy support is the most common reason patients on NAD+, tirzepatide or semaglutide add MOTS-c. Tell your provider everything you are taking and they will confirm the combination is appropriate.
How fast will I notice anything?
Some patients report steadier energy or easier training within the first few weeks. Others notice little. Effects are gradual and patient-specific, and individual results vary.
When should I inject it?
Many patients take it in the morning or before a workout. Under the skin, in the fat layer of the belly or upper thigh. Your provider sets the timing and shows you where in the portal.
I compete in tested sport. Can I use it?
Check your league's prohibited list before you start. Anti doping rules cover many metabolic peptides, and if you are drug tested for a sport, ask your league first.
What if I miss a dose?
Take the next dose on your regular schedule. Do not double up. Message your provider in the portal if you have questions.
Who fills the prescription?
A U.S. licensed compounding pharmacy partnered with PepHaus. Every vial ships with a Certificate of Analysis showing purity and concentration, ready to use. No mystery powder, no mixing, no guessing.
Where is MOTS-c available?
MOTS-c is available in all 50 states. Eligibility is confirmed during your intake, before any charge.
Is compounded MOTS-c FDA approved?
No. Compounded medications are prepared for individual patients by licensed pharmacies under a provider's prescription and are not FDA approved products. Every PepHaus vial ships with a Certificate of Analysis.
Do I need insurance? Can I cancel?
No insurance needed. One flat price covers the provider visit, the medication, supplies and shipping. Cancel anytime from your dashboard, no phone call.

Four steps. No waiting room.

Step 1: a five minute online visit on your phone, no appointment
STEP 01
Start my order

A short online intake. No waiting room, no phone tag.

Step 2: a U.S. licensed provider in your state reviews your intake
STEP 02
A provider reviews it

A U.S. licensed provider decides if MOTS-c is appropriate for you. $0 charged during this step.

Step 3: medication compounded by a licensed U.S. pharmacy and shipped cold to your door
STEP 03
Charged only if prescribed

If approved, your card is charged and the pharmacy prepares your first shipment.

Step 4: message your PepHaus care team anytime in the patient portal
STEP 04
It ships to your door

Free expedited shipping, every time, including refills. Message your provider anytime.

Ready when you are.

Prescribed by a U.S. licensed provider and shipped cold to your door.

Start my order
×Product detail, zoomed
Scroll to see the detail · tap × to close